愁肠百结（愁腸百結）　

◎ 愁肠百结 chóucháng-bǎijié

[weighed down with anxiety;it is as if the worries were tied in knots to one another] 忧愁的心肠绕成了 一百个结。形容焦躁、痛苦、忧伤之极